The EyeCare Update

The Benefits of Preservative Free Drops
  • Benzalkonium chloride (BAK) is the most frequently used preservative in preserved eye drops. BAK can induce corneal and conjunctival epithelial cell apoptosis, damage corneal nerves, delay wound healing, interfere with tear film stability and cause loss of goblet cells.3
  • The negative symptoms experienced through the use of BAK-preserved drops may impact adherence to the prescribed treatment or management regime.4
  • Preservative-free tear replacement is preferred in cases of frequent and chronic application.5
  • Patients with Dry Eye Disease (DED), especially those with severe DED who require dosing over 4 times daily with lubricants or who use ocular lubricants in conjunction with other chronic topical therapies such as glaucoma medications, should avoid the use of ocular lubricants containing preservative.3
HYLO-Tear and HYLO-Forte Price Comparison
ProductHYLO TearHYLO ForteEvolve HAHyabakThealoz Duo
Drug Tariff price1£8.50£9.50£5.99£8.99£7.99
Average duration of scripts (days)30.3130.6519.7827.0725.55
Annual cost to ICS per patient£102.36£111.85£110.53£128.43£107.73

 

*Analysed data for preservative free (PF) ocular lubricants from Cegedim’s THIN database, Jan 2020-Dec 2020 (Representative of 400+ GP practices & 3.2M patient population)

The Benefits of Preservative Free Drops
  • Benzalkonium chloride (BAK) is the most frequently used preservative in preserved eye drops. BAK can induce corneal and conjunctival epithelial cell apoptosis, damage corneal nerves, delay wound healing, interfere with tear film stability and cause loss of goblet cells.3
  • The negative symptoms experienced through the use of BAK-preserved drops may impact adherence to the prescribed treatment or management regime.4
  • Preservative-free tear replacement is preferred in cases of frequent and chronic application.5
  • Patients with Dry Eye Disease (DED), especially those with severe DED who require dosing over 4 times daily with lubricants or who use ocular lubricants in conjunction with other chronic topical therapies such as glaucoma medications, should avoid the use of ocular lubricants containing preservative.3